Biogenic Analysis
Histamine
Histamine in the presence of Putrescine and Cadaverine can cause scombroid poisoning (presence of “scombrotoxine” in tuna or mackerel). Clinical symptoms of Histamine poisoning can be:
Cataneous | Gastroinestinal | Neurological | Other |
Rash | Neasea | Facial, neck | Hyptension |
Urticaria | Vomiting | Headache | Bronchospasm |
Edema | Diarrhea | Palpitations | Shock |
Facial | Abdominal cramps | Tingling, itching | |
Neck | Oral burning |
Analysis of Biogenic amines is normally performed by using a dedicated amino acid analyser equipped with a special column and a special set of buffers. If applicable samples can also be tested according to an in-house developed HPLC-method for Tryptophan based Biogenic amines (e.g. tryptamine, 5-OH-tryptamine or serotonin).